From Teletraan I: The Transformers Wiki

The name Optimus Prime has been assigned to several different characters:

• 1984 — Optimus Prime, the original version of the Autobot Commander from Generation 1. For toys of this character, see Optimus Prime (G1) toys.

• 2000 — Optimus Prime, the Autobot commander fire truck from Robots in Disguise.

• 2002 — Optimus Prime, Autobot Commander truck from the Unicron Trilogy series.

• 2003 — Optimus Prime, an Autobot commander killed by Unicron and sent into another dimension during the Dreamwave Armada comic's "Worlds Collide" storyline.

• 2004 — Optimus Prime is a Spy Changer from the Universe series.

• 2004 — Optimus Prime, whose corpse was cloned and tortured by Unicron to create Nemesis Prime, is from the Universe series.

• 2007 — Optimus Prime, commander of the Autobots from the Transformers live-action movie continuity.

• 2007 — Optimus Prime, a younger and less experienced leader of the Autobots from the Animated continuity.

• 2008 — Optimus Prime, the despotic leader of the evil Autobots in the "Shattered Glass" alternate universe.

Optimus Prime is not to be confused with:

• Other uses of the name "Optimus"

• Other uses of the name "Prime"

Additionally, Optimus Prime is not to be confused with the real-life persons:

• Mr. Optimus Prime, a well-known Transfan and National Guardsman who legally changed his name to Optimus Prime. Hey, did you hear he went to Iraq? Pretty cool huh! (Repeat 6 million times.)